Indeed, fatigue is one of the first signs of vitamin B12 deficiency
In fact if he is open minded, you might just enlighten him
In mice, a high-Se diet increased TCR signaling in CD4 + T cells, increased IL-2 expression, shifted the Th1/Th2 balance toward a Th1 phenotype, higher levels of interferon- (IFN-) and CD40 ligand (60)
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Is fat dissolving painful